CASE-REPORT - ACYCLOVIR NEUROTOXICITY AND NEPHROTOXICITY - THE ROLE FOR HEMODIALYSIS

被引：42
作者：
KRIEBLE, BF
RUDY, DW
GLICK, MR
CLAYMAN, MD
机构：
[1] Nephrology Section, Fesler Hall, Indiana Univ. School of Medicine, Indianapolis, IN 46202-5116
来源：
AMERICAN JOURNAL OF THE MEDICAL SCIENCES | 1993年 / 305卷 / 01期
关键词：
ACUTE RENAL FAILURE; ACYCLOVIR; CRYSTALLURIA; HEMODIALYSIS; NEPHROTOXICITY; NEUROTOXICITY;
D O I：
10.1097/00000441-199301000-00007
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was associated with a reduction in plasma acyclovir concentration. Acute hemodialysis therapy should be considered in cases of serious neurotoxicity secondary to acyclovir, especially when accompanied by renal failure.
引用
收藏
页码：36 / 39
页数：4
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