CASE-REPORT - ACYCLOVIR NEUROTOXICITY AND NEPHROTOXICITY - THE ROLE FOR HEMODIALYSIS

被引：42

作者：

KRIEBLE, BF

RUDY, DW

GLICK, MR

CLAYMAN, MD

机构：

[1] Nephrology Section, Fesler Hall, Indiana Univ. School of Medicine, Indianapolis, IN 46202-5116

来源：

AMERICAN JOURNAL OF THE MEDICAL SCIENCES | 1993年 / 305卷 / 01期

关键词：

ACUTE RENAL FAILURE; ACYCLOVIR; CRYSTALLURIA; HEMODIALYSIS; NEPHROTOXICITY; NEUROTOXICITY;

D O I：

10.1097/00000441-199301000-00007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was associated with a reduction in plasma acyclovir concentration. Acute hemodialysis therapy should be considered in cases of serious neurotoxicity secondary to acyclovir, especially when accompanied by renal failure.

引用

页码：36 / 39

页数：4

共 29 条

[1] ACYCLOVIR AND NEUROLOGIC MANIFESTATIONS [J].