POST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINE

被引:2
|
作者
Das, Vidyanand [1 ]
Singh, Dharmendra [2 ]
Murti, Krishna [3 ]
Das, Sushmita [2 ]
Das, Pradeep [2 ]
Pandey, Krishna [1 ]
机构
[1] Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
[2] Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Mol Biol, Patna, Bihar, India
[3] Natl Inst Pharm & Educ Res, Dept Pharm Practice, Hajipur, Bihar, India
关键词
PKDL; VL; Miltefosine; Ulcer; Kala-Azar Elimination Program;
D O I
10.3844/ajidsp.2014.50.55
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and PKDL by 2018. PKDL diagnosis and management has not been addressed properly. In this case report we have described a case of PKDL with ulcer and atypical presentation who was subsequently diagnosed by demonstration of Leishmania donovani bodies in the skin snips through microscopy, kinetoplast-DNA nested PCR and clinically. The patient was treated with miltefosine capsules in the dose of 50 mg twice-aday for twelve-weeks and responded completely. This case report assumes great importance as prompt diagnosis and treatment of PKDL is essential in the kala-azar elimination program.
引用
收藏
页码:50 / 55
页数:6
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