POST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINE
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作者:
Das, Vidyanand
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Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Das, Vidyanand
[1
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Singh, Dharmendra
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Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Mol Biol, Patna, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Singh, Dharmendra
[2
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Murti, Krishna
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Natl Inst Pharm & Educ Res, Dept Pharm Practice, Hajipur, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Murti, Krishna
[3
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Das, Sushmita
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Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Mol Biol, Patna, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Das, Sushmita
[2
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Das, Pradeep
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Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Mol Biol, Patna, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Das, Pradeep
[2
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Pandey, Krishna
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Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, IndiaIndian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
Pandey, Krishna
[1
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机构:
[1] Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Clin Med, Patna 800007, Bihar, India
[2] Indian Council Med Res, Rajendra Mem Res Inst Med Sci, Dept Mol Biol, Patna, Bihar, India
Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and PKDL by 2018. PKDL diagnosis and management has not been addressed properly. In this case report we have described a case of PKDL with ulcer and atypical presentation who was subsequently diagnosed by demonstration of Leishmania donovani bodies in the skin snips through microscopy, kinetoplast-DNA nested PCR and clinically. The patient was treated with miltefosine capsules in the dose of 50 mg twice-aday for twelve-weeks and responded completely. This case report assumes great importance as prompt diagnosis and treatment of PKDL is essential in the kala-azar elimination program.
机构:
Indian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
Pandey, Krishna
Pal, Biplab
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Lovely Profess Univ, Dept Pharmacol, Jalandhar Delhi GT Rd, Phagwara, Punjab, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
Pal, Biplab
Topno, Roshan Kamal
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Indian Council Med Res, Dept Epidemiol, Rajendra Mem Res Inst Med Sci, Patna, Bihar, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
Topno, Roshan Kamal
Lal, Chandra Shekhar
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Indian Council Med Res, Dept Biochem, Rajendra Mem Res Inst Med Sci, Patna, Bihar, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
Lal, Chandra Shekhar
Das, Vidya Nand Rabi
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Indian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
Das, Vidya Nand Rabi
Das, Pradeep
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Indian Council Med Res, Dept Mol Biol, Rajendra Mem Res Inst Med Sci, Patna, Bihar, IndiaIndian Council Med Res, Dept Clin Med, Rajendra Mem Res Inst Med Sci, Patna, Bihar, India
机构:
Bankura Sammilani Med Coll, Dept Dermatol, Bankura, IndiaLondon Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England
Das, Nilay K.
Flor, Raul de la
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Pharmidex Pharmaceut Serv Ltd, London, EnglandLondon Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England
Flor, Raul de la
Van Bocxlaer, Katrien
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London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England
Univ York, York Biomed Res Inst, Dept Biol, York, England
Univ York, York Biomed Res Inst, Skin Res Ctr, Hull York Med Sch, York, EnglandLondon Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England
Van Bocxlaer, Katrien
Croft, Simon L.
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London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, EnglandLondon Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England
Croft, Simon L.
Chatterjee, Mitali
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Inst Postgrad Med Educ & Res, Dept Pharmacol, Kolkata, IndiaLondon Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England