ION-CHANNEL-FORMING AND CATECHOLAMINE-RELEASING ACTIVITIES OF ELONGATED AND TRUNCATED ANALOGS OF TRICHOSPORIN-B

被引:2
|
作者
NAGAOKA, Y
IIDA, A
KAMBARA, T
ASAMI, K
TACHIKAWA, E
FUJITA, T
机构
[1] KYOTO UNIV, FAC PHARMACEUT SCI, SAKYO KU, KYOTO 60601, JAPAN
[2] KYOTO UNIV, INST CHEM RES, UJI, KYOTO 611, JAPAN
[3] IWATE MED UNIV, SCH MED, MORIOKA, IWATE 020, JAPAN
关键词
D O I
10.1039/c39950002203
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Examination of newly synthesized elongated and truncated analogues of the ion-channel-forming peptide, trichosporin-B-Vla (20 residues), for ion-channel-forming activity in lipid bilayer membranes and catecholamine secretion-inducing activity from adrenal chromaffin cells revealed that the natural compound has the optimal molecular length for both activities.
引用
收藏
页码:2203 / 2204
页数:2
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