MYOSIN-V IS PRESENT IN SYNAPTOSOMES FROM RAT CEREBRAL-CORTEX

被引：0
|
作者：
MANI, F
ESPREAFICO, EM
LARSON, RE
机构：
[1] USP,FAC MED,DEPT BIOQUIM,BR-14049900 RIBEIRAO PRET,BRAZIL
[2] USP,FAC MED,DEPT MORFOL,BR-14049900 RIBEIRAO PRET,BRAZIL
来源：
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH | 1994年 / 27卷 / 11期
关键词：
MYOSIN-V; SYNAPTOSOMES; SYNAPTOPHYSIN;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The subcellular localization in brain of an unconventional, calmodulin-binding myosin (myosin-V) found in neurons, astrocytes and other secretory cells of vertebrates has been investigated by probing Western blots of synaptic fractions from rat cerebral cortex with affinity-purified polyclonal antibodies against myosin-V. Myosin-V was detected in intact synaptosomes and in lysed synaptosomes associated with a particulate fraction. Our data suggest a role for brain myosin-V in membrane-cytoskeleton function in the synaptic region.
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页码：2639 / 2643
页数：5
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