PREDICTORS OF PREGNANCY SUCCESS IN REPEATED MISCARRIAGE

被引:18
作者
CAUCHI, MN
PEPPERELL, R
KLOSS, M
LIM, D
机构
[1] Royal Women's Hospital, Melbourne
关键词
D O I
10.1111/j.1600-0897.1991.tb00974.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Factors that may have a bearing on subsequent pregnancy success or failure in patients with recurrent abortion were examined in 165 women with a history of three or more consecutive miscarriages in the first trimester. The overall success rate was 67.9%. Factors that were found to correlate significantly with success rate were length of abortion history, total number of abortions, interval from last miscarriage to present pregnancy, and whether there was any degree of subfertility. Logistic regression analysis showed that the abortion x years index and maternal age accounted for all the variation observed in our data. Where all other known causes of abortions are excluded, recurrent aborters can be subdivided into two populations-namely, those with a relatively good prognosis characterized by a short abortion history and absence of subfertility problems, compared to those with a poor prognosis namely those with a long abortion history or presence of subfertility problems. These data clearly demonstrate major differences in success rates in women depending on the number of abortions and the length of abortion history (abortion x year index), particularly in women over the age of 30 years.
引用
收藏
页码:72 / 75
页数:4
相关论文
共 20 条
[1]  
BEER AE, 1985, EXP CLIN IMMUNOGENET, V2, P137
[2]  
BEER AE, 1981, AM J OBSTET GYNECOL, V141, P987
[3]   OBSTETRIC COMPLICATIONS ASSOCIATED WITH THE LUPUS ANTICOAGULANT [J].
BRANCH, DW ;
SCOTT, JR ;
KOCHENOUR, NK ;
HERSHGOLD, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 313 (21) :1322-1326
[4]   IMMUNIZATION BY PATERNAL LEUKOCYTES FOR PREVENTION OF PRIMARY HABITUAL ABORTION - RESULTS OF A MATCHED CONTROLLED TRIAL [J].
CARP, HJA ;
TODER, V ;
GAZIT, E ;
ORGAD, S ;
MASHIACH, S ;
NEBEL, L ;
SERR, DM .
GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 1990, 29 (01) :16-21
[5]   TREATMENT OF RECURRENT ABORTERS BY IMMUNIZATION WITH PATERNAL CELLS - CONTROLLED TRIAL [J].
CAUCHI, MN ;
LIM, D ;
YOUNG, DE ;
KLOSS, M ;
PEPPERELL, RJ .
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1991, 25 (01) :16-17
[6]  
CAUCHI MN, 1988, AM J REPROD IMMUNOL, V18, P28
[7]  
COULAM CB, 1987, AM J REPROD IMMUNOL, V14, P54
[8]   PATERNAL MONONUCLEAR CELL IMMUNIZATION THERAPY FOR REPEATED MISCARRIAGE - PREDICTIVE VARIABLES FOR PREGNANCY SUCCESS [J].
COWCHOCK, FS ;
SMITH, JB ;
DAVID, S ;
SCHER, J ;
BATZER, F ;
CORSON, S .
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1990, 22 (1-2) :12-17
[9]  
HILL JA, 1988, CONTRACEPTIVE RES TO, V11, P171
[10]   ANTIBODY TO CARDIOLIPIN AS A PREDICTOR OF FETAL DISTRESS OR DEATH IN PREGNANT PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS [J].
LOCKSHIN, MD ;
DRUZIN, ML ;
GOEI, S ;
QAMAR, T ;
MAGID, MS ;
JOVANOVIC, L ;
FERENC, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 313 (03) :152-156