Efficacy Comparison of Mannitol and Hypertonic Saline for Traumatic Brain Injury (TBI) Treatment

被引：3

作者：

Arifianto, Muhammad Reza ^{[1
]}

Ma'ruf, Achmad Zuhro ^{[2
]}

Ibrahim, Arie ^{[3
]}

机构：

[1] Kanudjoso Djatiwibowo Hosp, Balikpapan, Indonesia

[2] Kanudjoso Djatiwibowo Hosp, Dept Neurosurg, Balikpapan, Indonesia

[3] Mulawarman Univ, AW Syahranie Hosp, Fac Med, Dept Neurosurg, Samarinda, Indonesia

来源：

BALI MEDICAL JOURNAL | 2016年 / 5卷 / 03期

关键词：

Traumatic brain injury; increased intracranial pressure; comparison; Mannitol; hypertonic saline;

D O I：

10.15562/bmj.v5i3.281

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Traumatic Brain Injury (TBI) case is commonly found in the emergency room. TBI accompanied by increased intracranial pressure (ICP) is a neurological emergency that requires prompt and appropriate management. Hyperosmolar fluid is the main treatment in the initial management of increased ICP. Mannitol and hypertonic saline are hyperosmolar fluids which are generally used. There is no specific recommendation regarding the choice between the two fluids. From the current studies indicate that both fluids are equally effective in reducing ICP. Regarding the superiority between the two fluids, it is difficult to determine because of the heterogeneity of the studies that exist. Therefore, clinicians should choose between hyperosmolar fluids based on indications and contraindications exist in TBI patients.

引用

页码：170 / 176

页数：7

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