MITOCHONDRIAL TARGETING SEQUENCES - WHY NON-AMPHIPHILIC PEPTIDES MAY STILL BE AMPHIPHILIC

被引：40

作者：

GAVEL, Y

NILSSON, L

VONHEIJNE, G

机构：

[1] KAROLINSKA INST,DEPT MED BIOPHYS,S-10401 STOCKHOLM 60,SWEDEN

[2] KAROLINSKA INST,HUDDINGE HOSP,CTR BIOTECHNOL,DEPT MOLEC BIOL,S-14186 HUDDINGE,SWEDEN

来源：

FEBS LETTERS | 1988年 / 235卷 / 1-2期

关键词：

D O I：

10.1016/0014-5793(88)81257-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：173 / 177

页数：5

共 10 条

[1] ARTIFICIAL MITOCHONDRIAL PRESEQUENCES [J].

ALLISON, DS ;

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[2] SEQUENCES FROM A PROKARYOTIC GENOME OR THE MOUSE DIHYDROFOLATE-REDUCTASE GENE CAN RESTORE THE IMPORT OF A TRUNCATED PRECURSOR PROTEIN INTO YEAST MITOCHONDRIA [J].

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SCHATZ, G .

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[3] ANALYSIS OF MEMBRANE AND SURFACE PROTEIN SEQUENCES WITH THE HYDROPHOBIC MOMENT PLOT [J].

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WALL, R .

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[4] THE ORNITHINE TRANSCARBAMYLASE LEADER PEPTIDE DIRECTS MITOCHONDRIAL IMPORT THROUGH BOTH ITS MIDPORTION STRUCTURE AND NET POSITIVE CHARGE [J].

HORWICH, AL ;

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FENTON, WA ;

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JOURNAL OF CELL BIOLOGY, 1987, 105 (02) :669-677

[5]

HUBBARD RE, 1987, STRUCTURE DYNAMICS F, V1

[6] A CYTOSOLIC PROTEIN CONTAINS A CRYPTIC MITOCHONDRIAL TARGETING SIGNAL [J].

HURT, EC ;

SCHATZ, G .

NATURE, 1987, 325 (6104) :499-503

[7] A CHEMICALLY SYNTHESIZED PRE-SEQUENCE OF AN IMPORTED MITOCHONDRIAL PROTEIN CAN FORM AN AMPHIPHILIC HELIX AND PERTURB NATURAL AND ARTIFICIAL PHOSPHOLIPID-BILAYERS [J].

ROISE, D ;

HORVATH, SJ ;

TOMICH, JM ;

RICHARDS, JH ;

SCHATZ, G .

EMBO JOURNAL, 1986, 5 (06) :1327-1334

[8]

ROISE D, 1988, J BIOL CHEM, V263, P4509

[9] AMPHIPHILICITY IS ESSENTIAL FOR MITOCHONDRIAL PRESEQUENCE FUNCTION [J].

ROISE, D ;

THEILER, F ;

HORVATH, SJ ;

TOMICH, JM ;

RICHARDS, JH ;

ALLISON, DS ;

SCHATZ, G .

EMBO JOURNAL, 1988, 7 (03) :649-653

[10] MITOCHONDRIAL TARGETING SEQUENCES MAY FORM AMPHIPHILIC HELICES [J].

VONHEIJNE, G .

EMBO JOURNAL, 1986, 5 (06) :1335-1342

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