ACTH-INDUCED HYPERALGESIA IN RATS

被引：83
作者：
BERTOLINI, A
POGGIOLI, R
FERRARI, W
机构：
[1] Institute of Pharmacology, University of Modena, Modena, I-41100
来源：
EXPERIENTIA | 1979年 / 35卷 / 09期
关键词：
D O I：
10.1007/BF01963298
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The injection of ACTH 1-24 into the cerebral ventricles in rats markedly reduces the reaction time in the hotplate test and the nociception threshold in the tail-stimulation test. Morphine antagonizes and naloxone potentiates this hyperalgesic effect of ACTH. It is proposed that ACTH peptides play a physiological role in nociception. © 1979 Birkhäuser Verlag.
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页码：1216 / 1217
页数：2
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