VIRUCIDAL EFFICACY OF THE NEWER QUATERNARY AMMONIUM-COMPOUNDS

被引：34
|
作者：
KENNEDY, MA
MELLON, VS
CALDWELL, G
POTGIETER, LND
机构：
[1] Department of Comparative Medicine, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37901-1071
来源：
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION | 1995年 / 31卷 / 03期
关键词：
D O I：
10.5326/15473317-31-3-254
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The virucidal activity of several disinfectants containing newer generation quaternary ammonium compounds (QACs) as their active ingredients was evaluated. Disinfectants were used at the manufacturers' recommended dilutions with isolates of feline herpesvirus, feline calicivirus, and canine parvovirus, and a contact time of 10 minutes at room temperature. Detoxification of virus/disinfectant solutions was done by dialysis prior to virus assay in cell cultures. Two of four disinfectants completely inactivated feline herpesvirus, and two significantly reduced the titer of this virus. None of the disinfectants that were tested completely inactivated feline calicivirus. Canine parvovirus was not inactivated significantly by any of the QAC disinfectants. Sodium hypochlorite completely inactivated all viruses.
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页码：254 / 258
页数：5
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