INFLUENCE OF CAPILLARY DIMENSIONS ON THE PERFORMANCE OF A COAXIAL CAPILLARY ELECTROPHORESIS ELECTROSPRAY MASS-SPECTROMETRY INTERFACE

被引：23

作者：

TETLER, LW ^{[1
]}

COOPER, PA ^{[1
]}

POWELL, B ^{[1
]}

机构：

[1] ZENECA SPECIALTIES,MANCHESTER M9 3DA,LANCS,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 700卷 / 1-2期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0021-9673(94)01171-A

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The dimensions of the capillaries used to construct a typical coaxial capillary electrophoresis-mass spectrometry (CE-MS) interface, i.e. the inner diameter, the outer diameter and the wall thickness, have been shown to affect the performance of the CE-MS system. The influence of these parameters has been investigated in both MS and MS-MS modes. The initial results indicate that by reducing all the sheath capillaries' dimensions and the CE capillary outer diameter, better operation and increased sensitivity can be achieved. The capillary arrangement which gives optimum sensitivity and stable operation has been suggested.

引用

页码：21 / 26

页数：6

共 4 条

[1]

LEE ED, 1988, 36TH P ASMS C MASS S, P1085

[2]

MINARD RD, 1988, 36TH P ASMS C MASS S, P950

[3] COMPARISON OF LIQUID-JUNCTION AND COAXIAL INTERFACES FOR CAPILLARY ELECTROPHORESIS MASS-SPECTROMETRY WITH APPLICATION TO COMPOUNDS OF CONCERN TO THE AQUACULTURE INDUSTRY [J].