THE BINKHORST MEDAL LECTURE - BIOLOGIC RELATIONSHIP BETWEEN POLY(METHYL METHACRYLATE) INTRAOCULAR LENSES AND UVEAL TISSUE

被引：35
作者：
OBSTBAUM, SA
机构：
来源：
JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1992年 / 18卷 / 03期
关键词：
BIOCOMPATIBILITY; BLOOD-OCULAR BARRIER; CAPSULAR BAG IMPLANTATION; FOREIGN BODY INFLAMMATORY REACTION; IRIS CHAFING; PIGMENTARY DISPERSION; SURFACE MODIFICATION; TISSUE-IMPLANT INTERFACE;
D O I：
10.1016/S0886-3350(13)80897-8
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Implantation of a poly(methyl methacrylate) (PMMA) intraocular lens (IOL) after cataract surgery is associated with breakdown of the blood-ocular barrier and a foreign body inflammatory response. Although the material is biocompatible, it is not inert. The history of PMMA IOL implantation has reflected mechanical, chemical, and immunological interactions between the IOL and ocular tissues. The common link in these events is instability of the blood-ocular barrier. In this lecture, I discuss the nature of these interactions and present evidence that currently investigated methods of surface modification and capsular bag IOL implantation are effective in stabilizing the blood-ocular barrier.
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页码：219 / 231
页数：13
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