Applications of Copolymeric Nanoparticles in Drug Delivery Systems

被引:49
|
作者
Danafar, H. [1 ,2 ]
机构
[1] Zanjan Univ Med Sci, Zanjan Pharmaceut Nanotechnol Res Ctr, Zanjan, Iran
[2] Zanjan Univ Med Sci, Dept Med Chem, Sch Pharm, POB 45195-1338, Zanjan 4513956184, Iran
关键词
block copolymer; drug delivery system; hydrogels; micelles; nanoparticles;
D O I
10.1055/s-0042-109865
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Nanoparticles have outstanding compensate compared with other drug carriers, as a result of their small particle size and bulky and changeable surface. Recently, block copolymers have get imaginary movement on the continuing research in the area of drug delivery technology, because of their potential to afford a biomaterial having an extensive series of amphiphilic personality, in addition to targeting the drugs to specific position. Block copolymers are prepared up of blocks of different polymerized monomers. Between the block copolymers, amphiphilic block copolymers can self-assemble to form nano-sized vehicles, for example micelles, liposomes, polymerases and hydrogels in aqueous or non-aqueous media. This review evaluated the synthesis, construction, and major applications of amphiphilic block copolymer and analogous vehicles in order to provide an overview of the present features of functionalized block copolymers for drug delivery applications.
引用
收藏
页码:506 / 519
页数:14
相关论文
共 50 条
  • [41] Functionalized gold nanoparticles for drug delivery applications
    Thambiraj, S.
    Hema, S.
    Shankaran, D. Ravi
    MATERIALS TODAY-PROCEEDINGS, 2018, 5 (08) : 16763 - 16773
  • [42] Fabrication, Modeling and Characterization of Multi-Crosslinked Methacrylate Copolymeric Nanoparticles for Oral Drug Delivery
    Ngwuluka, Ndidi C.
    Pillay, Viness
    Choonara, Yahya E.
    Modi, Girish
    Naidoo, Dinesh
    du Toit, Lisa C.
    Kumar, Pradeep
    Ndesendo, Valence M. K.
    Khan, Riaz A.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2011, 12 (09): : 6194 - 6225
  • [43] Dendritic systems in drug delivery applications
    Jain, Narendra K.
    Asthana, Abhay
    EXPERT OPINION ON DRUG DELIVERY, 2007, 4 (05) : 495 - 512
  • [44] Drug delivery systems for intraocular applications
    Bourges, J. -L.
    Touchard, E.
    Kowalczuk, L.
    Berdugo, M.
    Thomas-Doyle, A.
    Bochot, A.
    Gomez, A.
    Azan, F.
    Gurny, R.
    Behar-Cohen, F.
    JOURNAL FRANCAIS D OPHTALMOLOGIE, 2007, 30 (10): : 1070 - 1088
  • [45] Drug Delivery Systems for Dental Applications
    Ficai, Denisa
    Sandulescu, Mihai
    Ficai, Anton
    Andronescu, Ecaterina
    Yetmez, Mehmet
    Agrali, Omer B.
    Elemek, Eser
    Gunduz, Oguzhan
    Sahin, Yesim M.
    Oktar, Faik N.
    CURRENT ORGANIC CHEMISTRY, 2017, 21 (01) : 64 - 73
  • [46] Advance of Amphiphilic Block Copolymeric Micelles as Drug Delivery
    Jiao, Zhen
    Wang, Xing
    Chen, Zhiming
    ASIAN JOURNAL OF CHEMISTRY, 2013, 25 (04) : 1765 - 1769
  • [47] Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy
    Narmani, Asghar
    Jahedi, Roghayyeh
    Bakhshian-Dehkordi, Ehsan
    Ganji, Saeid
    Nemati, Mahnaz
    Ghahramani-Asl, Ruhollah
    Moloudi, Kave
    Hosseini, Seyed Mohammad
    Bagheri, Hamed
    Kesharwani, Prashant
    Khani, Ali
    Farhood, Bagher
    Sahebkar, Amirhossein
    EXPERT OPINION ON DRUG DELIVERY, 2023, 20 (07) : 937 - 954
  • [48] Novel Applications in Controlled Drug Delivery Systems by Integrating Osmotic Pumps and Magnetic Nanoparticles
    Navarro-Tumar, David
    Garcia-Merino, Belen
    Gonzalez-Fernandez, Cristina
    Ortiz, Inmaculada
    San-Roman, Ma. -Fresnedo
    Bringas, Eugenio
    SENSORS, 2024, 24 (21)
  • [49] Preparation and Applications of Superparamagnetic Iron Oxide Nanoparticles in Novel Drug Delivery Systems: An Overview
    Hooshmand, Sara
    Hayat, Seyed Mohammad Gheibi
    Ghorbani, Ahmad
    Khatami, Mehrdad
    Pakravanan, Kimya
    Darroudi, Majid
    CURRENT MEDICINAL CHEMISTRY, 2021, 28 (04) : 777 - 799
  • [50] Polydopamine-based surface modification of copolymeric nanoparticles as a targeted drug delivery system for cancer therapy
    Zeng, Xiaowei
    Tao, Wei
    Liu, Gan
    Mei, Lin
    JOURNAL OF CONTROLLED RELEASE, 2017, 259 : E150 - E151