CORRECTION OF DUNCAN SYNDROME BY ALLOGENEIC BONE-MARROW TRANSPLANTATION

被引：37

作者：

WILLIAMS, LL

ROONEY, CM

CONLEY, ME

BRENNER, MK

KRANCE, RA

HESLOP, HE

机构：

[1] ST JUDE CHILDRENS RES HOSP, DEPT VIROL & MOLEC BIOL, MEMPHIS, TN 38105 USA

[2] ST JUDE CHILDRENS RES HOSP, DEPT IMMUNOL, MEMPHIS, TN 38105 USA

[3] UNIV TENNESSEE CTR HLTH SCI, DEPT PEDIAT, MEMPHIS, TN 38104 USA

来源：

LANCET | 1993年 / 342卷 / 8871期

关键词：

D O I：

10.1016/0140-6736(93)91413-G

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Duncan's syndrome (X-linked lymphoproliferative disorder) is a fatal immunodeficiency syndrome of unknown aetiology and without cure. We show that allogeneic bone marrow transplantation can correct the lethal immune deficits in a patient with this syndrome, We suggest that the primary abnormality in Duncan's syndrome is in bone-marrow derived cells.

引用

页码：587 / 588

页数：2

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