RESOLUTION OF RACEMIC MIXTURES OF HYOSCYAMINE AND COLCHICINE ON IMPREGNATED SILICA-GEL LAYERS

被引：17
|
作者：
BHUSHAN, R
ALI, I
机构：
[1] Departement of Chemistry, University of Roorkee, Roorkee
来源：
CHROMATOGRAPHIA | 1993年 / 35卷 / 9-12期
关键词：
THIN-LAYER CHROMATOGRAPHY; ENANTIOMER SEPARATION; (+/-)-HYOSCYAMINE; (+/-)-COLCHICINE; LAYER; L-ASPARTIC ACID IMPREGNATED;
D O I：
10.1007/BF02267937
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The enantiomeric resolution of (+/-)-hyoscyamine (atropine) and (+/-)-colchicine was achieved on silica gel impregnated with an optically active acid, L-aspartic acid (.03 %), as the chiral selector. The solvent system n-butanol chloroform acetic acid water (3:6:4:1, v/v), was found to resolve (+/-) mixtures.
引用
收藏
页码：679 / 680
页数：2
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