HISTOPATHOLOGY STUDIES IN HUMAN-MALIGNANT MELANOMAS OF THE CHOROID AFTER UNSUCCESSFUL TREATMENT WITH RU-106 RH-106 OPHTHALMIC APPLICATORS

被引：12

作者：

KLAUS, H

LOMMATZSCH, PK

FUCHS, U

机构：

[1] Augenklinik der Universität Leipzig, Leipzig, 0-7010

来源：

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | 1991年 / 229卷 / 05期

关键词：

D O I：

10.1007/BF00166314

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Choroidal malignant melanomas were examined after unsuccessful brachytherapy with Ru-106/Rh-106 ophthalmic plaques. The histologic findings were compared with those obtained in non-irradiated melanomas similar in size and location. Both groups revealed no significant clinical difference apart from the lower average age of the irradiated patients. Some of the histologic features (scar formation, changes in the distribution of cell types, rate of mitosis) represented reactions to irradiation. No single histologic feature was strongly correlated to the irradiated group. The phenomenon of radioinsensitivity observed in some malignant melanomas cannot be fully elucidated using conventional histologic methods.

引用

页码：480 / 486

页数：7

共 39 条

[1]

AUGSBURGER JJ, 1987, OPHTHALMOLOGY, V94, P1627

[2]

BETKO J, 1970, SZEMESZET, V107, P232

[3]

BROVKINA AF, 1986, ARCH OPHTHALMOL-CHIC, V104, P402

[4]

CHAR DH, 1983, ARCH OPHTHALMOL-CHIC, V101, P236

[5]

CHAR DH, 1982, ARCH OPHTHALMOL-CHIC, V100, P935

[6]

CHAR DH, 1983, OPHTHALMOLOGY, V90, P1219

[7]

CONSTABLE IJ, 1977, T OPHTHAL SOC UK, V97, P430

[8]

CRAWFORD JB, 1987, OPHTHALMOLOGY, V94, P639

[9]

DAVIDORF FH, 1977, T OPHTHAL SOC UK, V97, P394

[10] RADIOTHERAPY FOR CHOROIDAL MELANOMA - AN 18-YEAR EXPERIENCE WITH RADON [J].

DAVIDORF, FH ;

PAJKA, JT ;

MAKLEY, TA ;

KARTHA, MK .

ARCHIVES OF OPHTHALMOLOGY, 1987, 105 (03) :352-355

← 1 2 3 4 →