PROTEIN TRANSLOCATION - COMMON THEMES FROM BACTERIA TO MAN

被引：54
作者：
JUNGNICKEL, B [1 ]
RAPOPORT, TA [1 ]
HARTMANN, E [1 ]
机构：
[1] MAX DELBRUCK CTR MOLEC MED, D-13122 BERLIN, GERMANY
来源：
FEBS LETTERS | 1994年 / 346卷 / 01期
关键词：
PROTEIN TRANSPORT; ENDOPLASMIC RETICULUM; SECRETION; MEMBRANE BIOSYNTHESIS;
D O I：
10.1016/0014-5793(94)00367-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Protein transport across the endoplasmic reticulum membrane in eukaryotes and across the cytoplasmic membrane in bacteria have turned out to be highly related. The core component of the translocation apparatus is the Sec61/SecYp complex; at least two of its subunits are conserved in evolution. The Sec61/SecYp complex is involved in both co- and post-translational transport pathways. The two modes require probably distinct additional components.
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页码：73 / 77
页数：5
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