COMPARISON OF IMMUNE REPERTOIRES OF CHINESE AND PHILIPPINE PATIENTS INFECTED WITH SCHISTOSOMA-JAPONICUM

被引：14

作者：

KRESINA, TF

GUAN, XH

POSNER, M

RAMIREZ, B

OLDS, GR

机构：

[1] RES INST TROP MED,MANILA,PHILIPPINES

[2] ROGER WILLIAMS GEN HOSP,DEPT MED,HUMAN MONOCLONAL ANTIBODY LAB,PROVIDENCE,RI 02908

[3] NANJING MED COLL,NANJING,PEOPLES R CHINA

来源：

INFECTION AND IMMUNITY | 1991年 / 59卷 / 12期

关键词：

D O I：

10.1128/IAI.59.12.4698-4700.1991

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chinese and Philippine patients exhibited detectable titers of serum antibodies to Schistosoma japonicum worm and egg antigens. Western blot (immunoblot) data revealed differing antigenic profiles. Antigen inhibition studies showed low and high levels of cross-reactivity with anti-worm and anti-egg antibodies, respectively, derived from both Chinese and Philippine patients. Thus, anti-egg antibodies and egg antigens are more conserved than anti-worm antibodies and worm antigens.

引用

页码：4698 / 4700

页数：3