NEIGHBORING-GROUP PARTICIPATION IN THE CHROMIUM TRIOXIDE OXIDATION OF STEROIDAL 4,5-EPOXIDES - X-RAY MOLECULAR-STRUCTURE OF 4-BETA,6-BETA,17-BETA-TRIACETOXY-3-BETA,5-ALPHA-DIHYDROXYANDROSTANE

被引：4

作者：

FLAIH, N ^{[1
]}

HANSON, JR ^{[1
]}

HITCHCOCK, PB ^{[1
]}

机构：

[1] UNIV SUSSEX,SCH MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 05期

关键词：

D O I：

10.1039/p19910001085

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chromium trioxide oxidation of steroidal 3-beta-acetoxy-4-alpha,5-alpha-epoxides affords products in which the acetoxy group has migrated to the 4-beta-position whilst oxidation of the isomeric 4-beta,5-beta-epoxides affords 5-alpha-hydroxy-4-ketones without rearrangement. The effect of 3-chloro and 6-beta-acetoxy substituents is explored.

引用

页码：1085 / 1089

页数：5

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