CELL-ADHESION MOLECULES AND SIGNAL-TRANSDUCTION

被引：0
|
作者：
JARAMILLO, ML
BELL, JC
机构：
[1] UNIV OTTAWA, DEPT MED, OTTAWA, ON K1H 8M5, CANADA
[2] UNIV OTTAWA, DEPT BIOCHEM, OTTAWA, ON K1H 8M5, CANADA
来源：
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY | 1995年 / 7卷 / 35期
关键词：
CELL ADHESION MOLECULES; MYELIN ASSOCIATED GLYCOPROTEIN; NERVOUS SYSTEM; SIGNAL TRANSDUCTION;
D O I：
10.4052/tigg.7.205
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cell adhesion molecules (CAM) play key roles in the fundamental processes of growth and development, particularly in the nervous system. This review focuses on the evidence implicating the cadherin, integrin and immunoglobulin superfamily of cell adhesion molecules in various signal transduction pathways. In addition to modulating cell adhesion and migration, CAMs also serve to directly regulate the response to growth and differentiation factors. This review focuses on the role of CAMs and their signal transduction pathways, where known, in several developmentally regulated processes in the nervous system such as the induction of neural tissue, neuroblast migration, axon growth and guidance, and myelination.
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页码：205 / 221
页数：17
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