REGIONAL DIFFERENCES IN SENSITIVITY OF VESTIBULAR SENSORY EPITHELIA TO OTOTOXIC ANTIBIOTICS

被引：144
作者：
LINDEMAN, HH
机构：
[1] Otolaryngological Department, University of Gothenburg, Gothenburg
[2] Kir. klin., Lasarettet, Säffle
来源：
ACTA OTO-LARYNGOLOGICA | 1969年 / 67卷 / 2-3期
关键词：
D O I：
10.3109/00016486909125441
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
The effect of intratympanic application of streptomycin and parenteral injections of kanamycin upon the vestibular sensory epithelia have been studied with the surface specimen technique. Clear regional differences in vulnerability to these ototoxic antibiotics have been noticed. The sensory epithelia of the cristae ampullares were more vulnerable than the macula utriculi, which in turn was distinctly more vulnerable than the macula sacculi. The degenerative changes involved primarily the central parts of the crista epithelium and the striola of the maculae. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：177 / &
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