ACETOGENIC ISOQUINOLINE ALKALOIDS .72. (1R,3R)-1,3-DIMETHYL-8-HYDROXY-6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE - AN ENANTIOMERICALLY PURE BUILDING-BLOCK FOR THE SYNTHESIS OF NAPHTHYLISOQUINOLINE ALKALOIDS

被引：1

作者：

PETERS, K ^{[1
]}

PETERS, EM ^{[1
]}

BRINGMANN, G ^{[1
]}

KELLER, PA ^{[1
]}

SCHAFFER, M ^{[1
]}

机构：

[1] UNIV WURZBURG,INST ORGAN CHEM,D-97074 WURZBURG,GERMANY

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 1995年 / 50卷 / 07期

关键词：

CRYSTAL STRUCTURE; NAPHTHYLISOQUINOLINE ALKALOIDS; STEREOCHEMISTRY;

D O I：

10.1515/znb-1995-0729

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title compound was prepared by hydrogenolytic deprotection of the corresponding N-benzyl derivative, which had previously been synthesized by a Picted-Spengler condensation of the corresponding arylethylamine. It crystallizes from dichloromethane/methanol in the orthorhombic system, space group P2(1)2(1)2(1); a = 1305.7(2), b = 1400.3(3), c = 727.4(1) pm. Hydrogen bonds between Cl and OH and NH2 groups cause a three-dimensional arrangement.

引用

页码：1137 / 1139

页数：3

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