MICROBIAL HYDROXYLATION OF A DIHYDROARTEMISININ DERIVATIVE

被引：8

作者：

HU, YL

HIGHET, RJ

MARION, D

ZIFFER, H

机构：

[1] NIDDK,CHEM PHYS LAB,BETHESDA,MD 20892

[2] NHLBI,BIOPHYS CHEM LAB,BETHESDA,MD 20892

[3] CEN,RESONANCE MAGNET LAB,F-38041 GRENOBLE,FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 17期

关键词：

D O I：

10.1039/c39910001176

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The fungus Beauveria sulfurescens has been employed to convert the 14-methyl group of the phenylcarbamoyl of dihydroartemisinin to the corresponding 14-hydroxymethyl derivative; the structure of the product was established by mass and 2D NMR spectroscopy.

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页码：1176 / 1177

页数：2

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