COMPLEMENT COMPONENT-C1Q ACTIVITY AND ASCORBIC-ACID NUTRITURE IN GUINEA-PIGS

被引：9
作者：
HASKELL, BE
JOHNSTON, CS
机构：
来源：
AMERICAN JOURNAL OF CLINICAL NUTRITION | 1991年 / 54卷 / 06期
关键词：
ASCORBIC ACID; C1Q; COMPLEMENT; HYDROXYPROLINE;
D O I：
10.1093/ajcn/54.6.1228s
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
When guinea pigs are fed tissue-saturating amounts of ascorbate, C1q concentrations are significantly higher than in those animals fed only enough ascorbate for adequate growth and for the prevention of scurvy. C1q is the recognition protein of the classical complement pathway, a system of blood proteins that constitutes an important part of host defense against pathogens. The observed effect of ascorbate nutriture on C1q concentrations is consistent with the known role of ascorbic acid in hydroxyproline biosynthesis. C1q is a hydroxyproline-containing protein with structural similarities to collagen.
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收藏
页码：S1228 / S1228
页数：1
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