A STEREOSELECTIVE SYNTHESIS OF SPHINGOSINE, A PROTEIN KINASE-C INHIBITOR

被引：133
|
作者：
NIMKAR, S
MENALDINO, D
MERRILL, AH
LIOTTA, D
机构：
[1] EMORY UNIV,DEPT CHEM,ATLANTA,GA 30322
[2] EMORY UNIV,DEPT BIOCHEM,ATLANTA,GA 30322
来源：
TETRAHEDRON LETTERS | 1988年 / 29卷 / 25期
关键词：
D O I：
10.1016/0040-4039(88)85079-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
引用
收藏
页码：3037 / 3040
页数：4
相关论文
共 50 条
  • [1] PROTEIN KINASE-C REGULATION BY SPHINGOSINE LYSOSPHINGOLIPIDS
    BELL, RM
    LOOMIS, CR
    HANNUN, YA
    COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1988, 53 : 103 - 110
  • [2] EFFECTS OF SPHINGOSINE ON PROTEIN KINASE-C IN LYMPHOCYTES
    GROVE, DS
    MASTRO, AM
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1988, 29 : 153 - 153
  • [3] REGULATION OF PROTEIN KINASE-C BY SPHINGOSINE AND LYSOSPHINGOLIPIDS
    HANNUN, YA
    BELL, RM
    CLINICA CHIMICA ACTA, 1989, 185 (03) : 333 - 346
  • [4] SYNTHESIS OF FLUORINE-CONTAINING ISOSTERES OF SPHINGOSINE AS INACTIVATORS OF PROTEIN KINASE-C
    KOZIKOWSKI, AP
    WU, JP
    TETRAHEDRON LETTERS, 1990, 31 (30) : 4309 - 4312
  • [5] SPHINGOSINE REVERSES PROTEIN KINASE-C INHIBITION OF CELL-GROWTH
    HUANG, CL
    SHEY, J
    IVES, HE
    KIDNEY INTERNATIONAL, 1989, 35 (01) : 174 - 174
  • [6] INHIBITION OF PROTEIN KINASE-C BY SPHINGOSINE CORRELATES WITH THE PRESENCE OF POSITIVE CHARGE
    BOTTEGA, R
    EPAND, RM
    BALL, EH
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 164 (01) : 102 - 107
  • [7] USE OF SPHINGOSINE AS INHIBITOR OF PROTEIN-KINASE-C
    HANNUN, YA
    MERRILL, AH
    BELL, RM
    METHODS IN ENZYMOLOGY, 1991, 201 : 316 - 328
  • [8] A concise synthesis of a promising protein kinase C inhibitor:: D-erythro-sphingosine
    Pham, Van-Thoai
    Joo, Jae-Eun
    Tian, Yong-Shou
    Oh, Chang-Young
    Ham, Won-Hun
    ARCHIVES OF PHARMACAL RESEARCH, 2007, 30 (01) : 22 - 27
  • [9] A concise synthesis of a promising protein kinase C inhibitor: D-erythro-sphingosine
    Van-Thoai Pham
    Jae-Eun Joo
    Yong-Shou Tian
    Chang-Young Oh
    Won-Hun Ham
    Archives of Pharmacal Research, 2007, 30 : 22 - 27
  • [10] PROTEIN KINASE-C
    PARKER, PJ
    ULLRICH, A
    JOURNAL OF CELLULAR PHYSIOLOGY, 1987, : 53 - 56
12345