BIOGENESIS OF SYNAPTIC VESICLES

被引：0

作者：

KELLY, RB ^{[1
]}

BONZELIUS, F ^{[1
]}

CLEVES, A ^{[1
]}

CLIFTOGRADY, L ^{[1
]}

GROTE, E ^{[1
]}

HERMAN, G ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,HORMONE RES INST,SAN FRANCISCO,CA 94143

来源：

JOURNAL OF CELL SCIENCE | 1993年

关键词：

SYNAPTIC VESICLES; ENDOSOME; SYNAPTOBREVIN; VAMP; PC12; CELLS;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The basic endosomal recycling pathway can be modified to generate transcytotic vesicles, storage vesicles and synaptic vesicles. Sorting into synaptic vesicles requires specialized sorting information not present in the transcytotic and storage vesicle proteins. Using mutagenesis we have distinguished the signals for rapid endocytosis and SV targeting in synaptobrevin. Finally, we have evidence that synaptic vesicles can be generated from an endosomal compartment in vitro.

引用

页码：81 / 83

页数：3

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