RADIOFREQUENCY CATHETER ABLATION IN THE TREATMENT OF SUPRAVENTRICULAR TACHYCARDIA IN THE ELDERLY

被引:44
作者
EPSTEIN, LM [1 ]
CHIESA, N [1 ]
WONG, MN [1 ]
LEE, RJ [1 ]
GRIFFIN, JC [1 ]
SCHEINMAN, MM [1 ]
LESH, MD [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, SAN FRANCISCO, CA 94143 USA
关键词
D O I
10.1016/0735-1097(94)90377-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives. The purpose of this study was to evaluate the efficacy and safety of radiofrequency catheter ablation for the treatment of supraventricular tachycardias in an elderly (greater than or equal to 70 years of age) group of patients. Background. Supraventricular tachycardias are the most common form of cardiac arrhythmia and affect all age groups. Although usually well tolerated in youth, supraventricular tachycardias may be associated with disabling symptoms and have life threatening potential in the elderly. In addition, antiarrhythmic agents are less well tolerated and may be associated with a higher incidence of toxicity in the elderly. Methods. From May 1989 to March 1993, 454 patients underwent a radiofrequency catheter ablation procedure at the University of California, San Francisco, for the treatment of symptomatic supraventricular tachycardia. Sixty-seven of these patients were greater than or equal to 70 years of age and constituted the study group. Patients underwent one of the following catheter ablation procedures: complete atrioventricular (AV) junctional ablation for ventricular rate control in patients with atrial fibrillation (37 patients), AV node modification for the treatment of AV node reentrant tachycardia (17 patients), accessory pathway ablation (9 patients), ablation of the ''slow zone'' to cure atrial butter (4 patients) and atrial tachycardia ablation (1 patient). One patient underwent ablation for both AV node reentrant tachycardia and atrial flutter. Results. Success was achieved in 67 (98.5%) of 68 ablation procedures. There were no procedural or early deaths. The overall complication rate was 7.4%, and only one patient (1.5%) had long term sequelae (permanent cardiac pacing for complete heart black). At a mean (+/-SD) follow up of 22.1 +/- 12.9 months, 63 (94%) of 67 patients were alive, with no antiarrhythmic agents for the treatment of their presenting arrhythmia. Conclusions. In this series radiofrequency catheter ablation appears to be an effective and safe treatment option for elderly patients (greater than or equal to 70 years of age) with a variety of symptomatic, drug-resistant supraventricular tachycardias. Because of the high incidence of severe symptoms associated with tachycardic episodes, the expense and the possible severe proarrhythmic problems associated with antiarrhythmic medications in this age group, catheter ablation may be considered an early rather than a ''last resort'' treatment option.
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页码:1356 / 1362
页数:7
相关论文
共 29 条
[1]   BODY-COMPOSITION - PREDICTION OF NORMAL BODY POTASSIUM, BODY-WATER AND BODY-FAT IN ADULTS ON THE BASIS OF BODY HEIGHT, BODY-WEIGHT AND AGE [J].
BRUCE, A ;
ANDERSSON, M ;
ARVIDSSON, B ;
ISAKSSON, B .
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1980, 40 (05) :461-473
[2]  
BURCH GE, 1989, AM HEART J, V78, P700
[3]   DIAGNOSIS AND CURE OF THE WOLFF-PARKINSON-WHITE SYNDROME OR PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIAS DURING A SINGLE ELECTROPHYSIOLOGIC TEST [J].
CALKINS, H ;
SOUSA, J ;
ELATASSI, R ;
ROSENHECK, S ;
DEBUITLEIR, M ;
KOU, WH ;
KADISH, AH ;
LANGBERG, JJ ;
MORADY, F .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (23) :1612-1618
[4]  
Chu Edward, 1993, Journal of the American College of Cardiology, V21, p417A
[5]   SPONTANEOUS OCCURRENCE OF SYMPTOMATIC PAROXYSMAL ATRIAL-FIBRILLATION AND PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA IN UNTREATED PATIENTS [J].
CLAIR, WK ;
WILKINSON, WE ;
MCCARTHY, EA ;
PAGE, RL ;
PRITCHETT, ELC .
CIRCULATION, 1993, 87 (04) :1114-1122
[6]  
DYBKAER R, 1981, ACTA MED SCAND, V209, P1
[7]  
EPSTEIN LM, 1992, CIRCULATION, V86, P723
[8]  
GERSTENBLITH G, 1983, CIRCULATION, V68, P101
[9]  
GERSTENBLITH G, 1979, CIRC RES, V44, P517, DOI 10.1161/01.RES.44.4.517
[10]   DIMINISHED INOTROPIC RESPONSE BUT UNALTERED TOXICITY TO ACETYLSTROPHANTHIDIN IN THE SENESCENT BEAGLE [J].
GUARNIERI, T ;
SPURGEON, H ;
FROEHLICH, JP ;
WEISFELDT, ML ;
LAKATTA, EG .
CIRCULATION, 1979, 60 (07) :1548-1554