NEW SUBSTITUTED 4-THIAZOLIDINONE DERIVATIVES FOR POSSIBLE USE AS ANTITUMOR AGENTS

被引:0
|
作者
GIRGES, MM [1 ]
HANNA, MA [1 ]
机构
[1] MANSOURA UNIV,FAC SCI,MANSOURA 35516,EGYPT
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中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The use of 2-(phenazon-4-yl)imino-3-phenyl-4-thiazolidinone (I), as well as its arylidene derivatives IIa, b as key intermediates in synthesis of different heterocyclic derivatives (III-X) has been investigated with a view of evaluating antibacterial and antitumor activities of the products. While most of these products stimulated the growth of different types of bacteria under investigation, they inhibited or sometimes completely suppressed the tumor growth in Swiss albino mice.
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页码:477 / 483
页数:7
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