Update of Sepsis: Recent Evidences about Early Goal Directed Therapy

被引:8
作者
Cho, Woo Hyun [1 ]
机构
[1] Pusan Natl Univ, Pusan Natl Univ Yangsan Hosp, Sch Med, Dept Internal Med, 20 Geumo Ro, Yangsan 626787, South Korea
关键词
Sepsis; Shock; Septic; Therapeuticselements;
D O I
10.4046/trd.2015.78.3.156
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
nSevere sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements of early goal directed therapy contributed to the better outcome. Recent prospective and randomized trials suggested that some elements of early goal directed therapy did not have any effect on the outcome benefit. In this paper, recent articles about early goal directed therapy will be reviewed and the effectiveness of individual elements of early goal directed therapy will be discussed.
引用
收藏
页码:156 / 160
页数:5
相关论文
共 32 条
[21]   Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007 [J].
Lagu, Tara ;
Rothberg, Michael B. ;
Shieh, Meng-Shiou ;
Pekow, Penelope S. ;
Steingrub, Jay S. ;
Lindenauer, Peter K. .
CRITICAL CARE MEDICINE, 2012, 40 (03) :754-761
[22]   Effects of perfusion pressure on tissue perfusion in septic shock [J].
LeDoux, D ;
Astiz, ME ;
Carpati, CM ;
Rackow, EC .
CRITICAL CARE MEDICINE, 2000, 28 (08) :2729-2732
[23]   The epidemiology of sepsis in the United States from 1979 through 2000 [J].
Martin, GS ;
Mannino, DM ;
Eaton, S ;
Moss, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (16) :1546-1554
[24]   Multicenter Implementation of a Severe Sepsis and Septic Shock Treatment Bundle [J].
Miller, Russell R., III ;
Dong, Li ;
Nelson, Nancy C. ;
Brown, Samuel M. ;
Kuttler, Kathryn G. ;
Probst, Daniel R. ;
Allen, Todd L. ;
Clemmer, Terry P. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 188 (01) :77-82
[25]   Goal-Directed Resuscitation for Patients with Early Septic Shock [J].
Peake, Sandra L. ;
Delaney, Anthony ;
Bailey, Michael ;
Bellomo, Rinaldo ;
Cameron, Peter A. ;
Cooper, D. James ;
Higgins, Alisa M. ;
Holdgate, Anna ;
Howe, Belinda D. ;
Webb, Steven A. R. ;
Williams, Patricia .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (16) :1496-1506
[26]   Hydroxyethyl Starch 130/0.4 versus Ringer's Acetate in Severe Sepsis [J].
Perner, Anders ;
Haase, Nicolai ;
Guttormsen, Anne B. ;
Tenhunen, Jyrki ;
Klemenzson, Gudmundur ;
Aneman, Anders ;
Madsen, Kristian R. ;
Moller, Morten H. ;
Elkjaer, Jeanie M. ;
Poulsen, Lone M. ;
Bendtsen, Asger ;
Winding, Robert ;
Steensen, Morten ;
Berezowicz, Pawel ;
Soe-Jensen, Peter ;
Bestle, Morten ;
Strand, Kristian ;
Wiis, Jorgen ;
White, Jonathan O. ;
Thornberg, Klaus J. ;
Quist, Lars ;
Nielsen, Jonas ;
Andersen, Lasse H. ;
Holst, Lars B. ;
Thormar, Katrin ;
Kjaeldgaard, Anne-Lene ;
Fabritius, Maria L. ;
Mondrup, Frederik ;
Pott, Frank C. ;
Moller, Thea P. ;
Winkel, Per ;
Wetterslev, Jorn .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (02) :124-134
[27]   Management of severe sepsis in patients admitted to Asian intensive care units: prospective cohort study [J].
Phua, Jason ;
Koh, Younsuck ;
Du, Bin ;
Tang, Yao-Qing ;
Divatia, Jigeeshu V. ;
Tan, Cheng Cheng ;
Gomersall, Charles D. ;
Faruq, Mohammad Omar ;
Shrestha, Babu Raja ;
Nguyen Gia Binh ;
Arabi, Yaseen M. ;
Salahuddin, Nawal ;
Wahyuprajitno, Bambang ;
Tu, Mei-Lien ;
Abd Wahab, Ahmad Yazid Haji ;
Hameed, Akmal A. ;
Nishimura, Masaji ;
Procyshyn, Mark ;
Chan, Yiong Huak .
BMJ-BRITISH MEDICAL JOURNAL, 2011, 342
[28]   Whole Blood Lactate Kinetics in Patients Undergoing Quantitative Resuscitation for Severe Sepsis and Septic Shock [J].
Puskarich, Michael A. ;
Trzeciak, Stephen ;
Shapiro, Nathan I. ;
Albers, Andrew B. ;
Heffner, Alan C. ;
Kline, Jeffrey A. ;
Jones, Alan E. .
CHEST, 2013, 143 (06) :1548-1553
[29]   Early goal-directed therapy in the treatment of severe sepsis and septic shock. [J].
Rivers, E ;
Nguyen, B ;
Havstad, S ;
Ressler, J ;
Muzzin, A ;
Knoblich, B ;
Peterson, E ;
Tomlanovich, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (19) :1368-1377
[30]   LONG-TERM SURVIVAL AFTER INTENSIVE-CARE UNIT ADMISSION WITH SEPSIS [J].
SASSE, KC ;
NAUENBERG, E ;
LONG, A ;
ANTON, B ;
TUCKER, HJ ;
HU, TW .
CRITICAL CARE MEDICINE, 1995, 23 (06) :1040-1047