Update of Sepsis: Recent Evidences about Early Goal Directed Therapy

被引:8
作者
Cho, Woo Hyun [1 ]
机构
[1] Pusan Natl Univ, Pusan Natl Univ Yangsan Hosp, Sch Med, Dept Internal Med, 20 Geumo Ro, Yangsan 626787, South Korea
关键词
Sepsis; Shock; Septic; Therapeuticselements;
D O I
10.4046/trd.2015.78.3.156
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
nSevere sepsis and septic shock is a life-threatening disease. It is combined with multi-organ failure. In the past decade, early goal directed therapy has been proposed as an effective treatment strategy for better outcome. Recent epidemiologic studies showed that the outcome of sepsis has been improved with the introduction of early goal directed therapy. However, it is unclear which elements of early goal directed therapy contributed to the better outcome. Recent prospective and randomized trials suggested that some elements of early goal directed therapy did not have any effect on the outcome benefit. In this paper, recent articles about early goal directed therapy will be reviewed and the effectiveness of individual elements of early goal directed therapy will be discussed.
引用
收藏
页码:156 / 160
页数:5
相关论文
共 32 条
[1]   High versus Low Blood-Pressure Target in Patients with Septic Shock [J].
Asfar, Pierre ;
Meziani, Ferhat ;
Hamel, Jean-Francois ;
Grelon, Fabien ;
Megarbane, Bruno ;
Anguel, Nadia ;
Mira, Jean-Paul ;
Dequin, Pierre-Francois ;
Gergaud, Soizic ;
Weiss, Nicolas ;
Legay, Francois ;
Le Tulzo, Yves ;
Conrad, Marie ;
Robert, Rene ;
Gonzalez, Frederic ;
Guitton, Christophe ;
Tamion, Fabienne ;
Tonnelier, Jean-Marie ;
Guezennec, Pierre ;
Van der Linden, Thierry ;
Vieillard-Baron, Antoine ;
Mariotte, Eric ;
Pradel, Gael ;
Lesieur, Olivier ;
Ricard, Jean-Damien ;
Herve, Fabien ;
du Cheyron, Damien ;
Guerin, Claude ;
Mercat, Alain ;
Teboul, Jean-Louis ;
Radermacher, Peter .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (17) :1583-1593
[2]   Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study [J].
Blanco, Jesus ;
Muriel-Bombin, Arturo ;
Sagredo, Victor ;
Taboada, Francisco ;
Gandia, Francisco ;
Tamayo, Luis ;
Collado, Javier ;
Garcia-Labattut, Angel ;
Carriedo, Demetrio ;
Valledor, Manuel ;
De Frutos, Martin ;
Lopez, Maria-Jesus ;
Caballero, Ana ;
Guerra, Jose ;
Alvarez, Braulio ;
Mayo, Agustin ;
Villar, Jesus .
CRITICAL CARE, 2008, 12 (06)
[3]   Increasing mean arterial pressure in patients with septic shock:: Effects on oxygen variables and renal function [J].
Bourgoin, A ;
Leone, M ;
Delmas, A ;
Garnier, F ;
Albanèse, J ;
Martin, C .
CRITICAL CARE MEDICINE, 2005, 33 (04) :780-786
[4]   Albumin Replacement in Patients with Severe Sepsis or Septic Shock [J].
Caironi, Pietro ;
Tognoni, Gianni ;
Masson, Serge ;
Fumagalli, Roberto ;
Pesenti, Antonio ;
Romero, Marilena ;
Fanizza, Caterina ;
Caspani, Luisa ;
Faenza, Stefano ;
Grasselli, Giacomo ;
Iapichino, Gaetano ;
Antonelli, Massimo ;
Parrini, Vieri ;
Fiore, Gilberto ;
Latini, Roberto ;
Gattinoni, Luciano .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (15) :1412-1421
[5]   Epidemiology of sepsis: Recent advances [J].
Danai P. ;
Martin G.S. .
Current Infectious Disease Reports, 2005, 7 (5) :329-334
[6]   Dopamine versus norepinephrine in the treatment of septic shock: A meta-analysis [J].
De Backer, Daniel ;
Aldecoa, Cesar ;
Njimi, Hassane ;
Vincent, Jean-Louis .
CRITICAL CARE MEDICINE, 2012, 40 (03) :725-730
[7]   Comparison of Dopamine and Norepinephrine in the Treatment of Shock. [J].
De Backer, Daniel ;
Biston, Patrick ;
Devriendt, Jacques ;
Madl, Christian ;
Chochrad, Didier ;
Aldecoa, Cesar ;
Brasseur, Alexandre ;
Defrance, Pierre ;
Gottignies, Philippe ;
Vincent, Jean-Louis .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (09) :779-789
[8]  
Dellinger RP, 2013, INTENS CARE MED, V39, P165, DOI [10.1007/s00134-012-2769-8, 10.1097/CCM.0b013e31827e83af]
[9]   Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 [J].
Dellinger, R. Phillip ;
Levy, Mitchell M. ;
Carlet, Jean M. ;
Bion, Julian ;
Parker, Margaret M. ;
Jaeschke, Roman ;
Reinhart, Konrad ;
Angus, Derek C. ;
Brun-Buisson, Christian ;
Beale, Richard ;
Calandra, Thierry ;
Dhainaut, Jean-Francois ;
Gerlach, Herwig ;
Harvey, Maurene ;
Marini, John J. ;
Marshall, John ;
Ranieri, Marco ;
Ramsay, Graham ;
Sevransky, Jonathan ;
Thompson, B. Taylor ;
Townsend, Sean ;
Vender, Jeffrey S. ;
Zimmerman, Janice L. ;
Vincent, Jean-Louis .
INTENSIVE CARE MEDICINE, 2008, 34 (01) :17-60
[10]   Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock [J].
Dellinger, RP ;
Carlet, JM ;
Masur, H ;
Gerlach, H ;
Calandra, T ;
Cohen, J ;
Gea-Banacloche, J ;
Keh, D ;
Marshall, JC ;
Parker, MM ;
Ramsay, G ;
Zimmerman, JL ;
Vincent, JL ;
Levy, MM .
CRITICAL CARE MEDICINE, 2004, 32 (03) :858-873