NEOMYCIN INHIBITS PLATELET FUNCTIONS AND INOSITOL PHOSPHOLIPID-METABOLISM UPON STIMULATION WITH THROMBIN, BUT NOT WITH IONOMYCIN OR 12-O-TETRADECANOYL-PHORBOL 13-ACETATE

被引：40
作者：
TYSNES, OB
STEEN, VM
HOLMSEN, H
机构：
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1988年 / 177卷 / 01期
关键词：
D O I：
10.1111/j.1432-1033.1988.tb14365.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：219 / 223
页数：5
相关论文
共 38 条
[1]  
AGRANOFF BW, 1983, J BIOL CHEM, V258, P2076
[2]  
Berridge M J, 1986, J Cell Sci Suppl, V4, P137
[3]   INOSITOL TRISPHOSPHATE, A NOVEL 2ND MESSENGER IN CELLULAR SIGNAL TRANSDUCTION [J].
BERRIDGE, MJ ;
IRVINE, RF .
NATURE, 1984, 312 (5992) :315-321
[4]   INOSITOL 1,4,5-TRIPHOSPHATE-INDUCED GRANULE SECRETION IN PLATELETS - EVIDENCE THAT THE ACTIVATION OF PHOSPHOLIPASE-C MEDIATED BY PLATELET THROMBOXANE RECEPTORS INVOLVES A GUANINE-NUCLEOTIDE BINDING PROTEIN-DEPENDENT MECHANISM DISTINCT FROM THAT OF THROMBIN [J].
BRASS, LF ;
SHALLER, CC ;
BELMONTE, EJ .
JOURNAL OF CLINICAL INVESTIGATION, 1987, 79 (04) :1269-1275
[5]   PHOSPHOINOSITIDES IN MITOGENESIS - NEOMYCIN INHIBITS THROMBIN-STIMULATED PHOSPHOINOSITIDE TURNOVER AND INITIATION OF CELL-PROLIFERATION [J].
CARNEY, DH ;
SCOTT, DL ;
GORDON, EA ;
LABELLE, EF .
CELL, 1985, 42 (02) :479-488
[6]   ROLE OF GUANINE-NUCLEOTIDE BINDING-PROTEIN IN THE ACTIVATION OF POLYPHOSPHOINOSITIDE PHOSPHODIESTERASE [J].
COCKCROFT, S ;
GOMPERTS, BD .
NATURE, 1985, 314 (6011) :534-536
[7]   ADP STIMULATES IP3 FORMATION IN HUMAN-PLATELETS [J].
DANIEL, JL ;
DANGELMAIER, CA ;
SELAK, M ;
SMITH, JB .
FEBS LETTERS, 1986, 206 (02) :299-303
[8]   12-O-TETRADECANOYLPHORBOL 13-ACETATE STIMULATES INOSITOL LIPID PHOSPHORYLATION IN INTACT HUMAN-PLATELETS [J].
DECOURCELLES, DD ;
ROEVENS, P ;
VANBELLE, H .
FEBS LETTERS, 1984, 173 (02) :389-393
[9]   DETERMINATION OF LEVELS OF GLYCOLYTIC-INTERMEDIATES AND NUCLEOTIDES IN PLATELETS BY PULSE-LABELING WITH [P-32] ORTHO-PHOSPHATE [J].
HOLMSEN, H ;
DANGELMAIER, CA ;
AKKERMAN, JWN .
ANALYTICAL BIOCHEMISTRY, 1983, 131 (01) :266-272
[10]   TIGHT COUPLING OF THROMBIN-INDUCED ACID HYDROLASE SECRETION AND PHOSPHATIDATE SYNTHESIS TO RECEPTOR OCCUPANCY IN HUMAN-PLATELETS [J].
HOLMSEN, H ;
DANGELMAIER, CA ;
RONGVED, S .
BIOCHEMICAL JOURNAL, 1984, 222 (01) :157-167
1234