RELEASE OF BETA-ENDORPHIN FROM RAT PITUITARY INVITRO

被引：30

作者：

PRZEWLOCKI, R

HOLLT, V

HERZ, A

机构：

[1] Department of Neuropharmacology, Max-Planck-Institut für Psychiatrie, D-8000 München 40

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1978年 / 51卷 / 02期

关键词：

Pituitary; β-Endorphin radioimmunoassay; β-Endorphin release;

D O I：

10.1016/0014-2999(78)90342-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The rate of release of β-endorphin immunoreactivity from the anterior lobe of the rat pituitary in vitro increased in response to potassium-induced depolarization in a calcium-dependent manner. Potassium-induced depolarization did not, however, change the rate of release from intermediate/posterior lobe. These findings provide support for the view that β-endorphin may have a humoral function and suggest that β-endorphin stores in discrete pituitary areas are regulated by different release mechanisms. © 1978.

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页码：179 / 183

页数：5

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