Placental expression of indoleamine 2,3-dioxygenase

被引:0
|
作者
Sedlmayr, Peter [1 ]
Blaschitz, Astrid [1 ]
机构
[1] Med Univ Graz, Ctr Mol Med, Inst Cell Biol Histol & Embryol, Graz, Austria
关键词
Pregnancy; feto-maternal tolerance; vascular endothelium; placenta; vasodilatation; kynurenine;
D O I
10.1007/s10354-012-0082-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review focuses on the placental expression of the tryptophan-degrading enzyme indoleamine 2,3-dioxygenase-1 (IDO1) and its potential roles, which may not only encompass immunosuppression and antimicrobial activity, but also vasodilation based on the endothelial expression on both sides of the feto-maternal interface.
引用
收藏
页码:214 / 219
页数:6
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