THERMODYNAMICS OF SOLVATION IN MIXED-SOLVENTS

Chemists have long recognized that changes in solvent have profound effects on the properties of chemical systems. However it is only in the past quarter of a century that theoretical models which will predict these effects have emerged. This article outlines the development of one such model and shows how it provides detailed information about the roles of the interactions between solvent and solute molecules in determining the thermodynamics of chemical systems.