A NEW EICOSAPENTAENOIC ACID FORMED FROM ARACHIDONIC-ACID IN THE CORALLINE RED ALGAE BOSSIELLA-ORBIGNIANA

被引：43

作者：

BURGESS, JR

DELAROSA, RI

JACOBS, RS

BUTLER, A

机构：

[1] UNIV CALIF SANTA BARBARA,DEPT BIOL SCI,SANTA BARBARA,CA 93106

[2] UNIV CALIF SANTA BARBARA,DEPT CHEM,SANTA BARBARA,CA 93106

来源：

LIPIDS | 1991年 / 26卷 / 02期

关键词：

D O I：

10.1007/BF02544012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aqueous extracts of the coralline red algae Bossiella orbigniana have been shown to catalyze the enzymatic oxidation of arachidonic acid to a previously unreported omega-6 eicosapentaenoic acid product. This unique fatty acid contains a conjugated tetraene with absorption maxima at 293, 306, and 321 nm, and was identified by spectral methods as 5(Z),8(Z),10(E),14(Z)-eicosapentaenoic acid. The compound was given the trivial name bosseopentaenoic acid. Under experimental conditions, production of bosseopentaenoic acid was linear up to 2 hr and dioxygen was consumed. Bosseopentaenoic acid, along with several other conjugated tetraenes, was also present in the algae endogenously as revealed by a comparison of the ultra-violet (UV) spectra and the high-performance liquid chromatographic (HPLC) pattern of the purified product and the organic extract of Bossiella.

引用

页码：162 / 165

页数：4

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