Hip structure analysis by DXA of teriparatide treatment: A 24-month follow-up clinical study

被引：4

作者：

Mochizuki, Takeshi ^{[1
]}

Yano, Koichiro ^{[2
]}

Ikari, Katsunori ^{[2
]}

Kawakami, Kosei ^{[1
]}

Hiroshima, Ryo ^{[1
]}

Koenuma, Naoko ^{[1
]}

Ishibashi, Mina ^{[1
]}

Shirahata, Toshikatsu ^{[3
]}

机构：

[1] Kamagaya Gen Hosp, Dept Rheumatol & Orthopaed Surg, Chiba, Japan

[2] Tokyo Womens Med Univ, Inst Rheumatol, Tokyo, Japan

[3] Chibanishi Gen Hosp, Dept Orthopaed Surg, Chiba, Japan

来源：

JOURNAL OF ORTHOPAEDICS | 2016年 / 13卷 / 04期

关键词：

Dual-energy X-ray absorptiometry; Hip structure analysis; Osteoporosis; Rheumatoid arthritis; Teriparatide;

D O I：

10.1016/j.jor.2016.09.001

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Objective: The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis. Methods: The study included 96 patients with postmenopausal osteoporosis and received 20 mu g TPTD daily. HSA was performed by dual-energy X-ray absorptiometry. Results: The percent changes from baseline for the cross-sectional moment of inertia, section modulus, buckling ratio, and femoral strength index based on HSA results were 9.8% (p < 0.01), 10.7%, 3.3%, and 14.9% (p < 0.01), respectively, at 24 months. Conclusion: Based on the HSA results obtained with DXA, TPTD was effective for hip structures. (C) 2016 Prof. PK Surendran Memorial Education Foundation. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.

引用

页码：414 / 418

页数：5

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