LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN' THROUGH INCREMENTAL CHANGES IN THE FREE-ENERGY OF UNFOLDING

被引：218

作者：

PANTOLIANO, MW ^{[1
]}

WHITLOW, M ^{[1
]}

WOOD, JF ^{[1
]}

DODD, SW ^{[1
]}

HARDMAN, KD ^{[1
]}

ROLLENCE, ML ^{[1
]}

BRYAN, PN ^{[1
]}

机构：

[1] GENEX CORP,GAITHERSBURG,MD 20877

来源：

BIOCHEMISTRY | 1989年 / 28卷 / 18期

关键词：

D O I：

10.1021/bi00444a012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7205 / 7213

页数：9

共 72 条

[1]

AGRO A F, 1972, European Journal of Biochemistry, V28, P89

[2] A GENETIC SCREEN FOR MUTATIONS THAT INCREASE THE THERMAL-STABILITY OF PHAGE-T4 LYSOZYME [J].

ALBER, T ;

WOZNIAK, JA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (03) :747-750

[3] CONTRIBUTIONS OF HYDROGEN-BONDS OF THR-157 TO THE THERMODYNAMIC STABILITY OF PHAGE-T4 LYSOZYME [J].

ALBER, T ;

SUN, DP ;

WILSON, K ;

WOZNIAK, JA ;

COOK, SP ;

MATTHEWS, BW .

NATURE, 1987, 330 (6143) :41-46

[4] HYDROGEN-BONDING IN GLOBULAR-PROTEINS [J].

BAKER, EN ;

HUBBARD, RE .

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1984, 44 (02) :97-179

[5] PROTEIN STABILITY CURVES [J].

BECKTEL, WJ ;

SCHELLMAN, JA .

BIOPOLYMERS, 1987, 26 (11) :1859-1877

[6] THERMODYNAMICS OF PROTEIN DENATURATION .2. MODEL OF REVERSIBLE DENATURATION + INTERPRETATIONS REGARDING STABILITY OF CHYMOTRYPSINOGEN [J].

BRANDTS, JF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (20) :4302-&

[7]

BRIGGS RG, 1978, BIOCHIM BIOPHYS ACTA, V537, P100, DOI 10.1016/0005-2795(78)90606-2

[8] CHARMM - A PROGRAM FOR MACROMOLECULAR ENERGY, MINIMIZATION, AND DYNAMICS CALCULATIONS [J].

BROOKS, BR ;

BRUCCOLERI, RE ;

OLAFSON, BD ;

STATES, DJ ;

SWAMINATHAN, S ;

KARPLUS, M .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1983, 4 (02) :187-217

[9] SITE-DIRECTED MUTAGENESIS AND THE ROLE OF THE OXYANION HOLE IN SUBTILISIN [J].

BRYAN, P ;

PANTOLIANO, MW ;

QUILL, SG ;

HSIAO, HY ;

POULOS, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (11) :3743-3745

[10]

BRYAN P N, 1986, Proteins Structure Function and Genetics, V1, P326

← 1 2 3 4 5 6 7 8 →