EFFECT OF IMMUNOCHEMOTHERAPY ON LYMPHOCYTE-RESPONSE OF PATIENTS WITH GASTRO-INTESTINAL CANCER

被引:5
|
作者
MASHIBA, H [1 ]
YOSHINAGA, H [1 ]
MATSUNAGA, K [1 ]
GOJOBORI, M [1 ]
FURUSAWA, M [1 ]
机构
[1] KYUSHU CANC CTR HOSP,DEPT GASTROINTESTINAL SURG,FUKUOKA,JAPAN
关键词
gastrointestinal cancer; host response; immunochemotherapy;
D O I
10.1002/jso.2930120312
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Patients with gastrointestinal cancer were treated with 5‐fluorouracil (5‐FU) in combination with a streptococcal preparation, OK‐432, or without OK‐432 before operation, and lymphocyte response to PHA was examined. Oral administration of 5‐FU with or without intramuscular injection of OK‐432 did not affect the response. However, treatment with cytostatic drugs in combination with OK‐432 markedly augmented the lymphocyte response to PHA, but the cytotoxic activity of lymphocytes was not elevated. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码:275 / 279
页数:5
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