CARBON-CARBON BOND FORMATION AT THE C-4 POSITION OF AN AZETIDIN-2-ONE RING BY INTERMOLECULAR RADICAL COUPLING REACTIONS - A ROUTE TO TRIBACTAMS

被引：19

作者：

PADOVA, A ^{[1
]}

ROBERTS, SM ^{[1
]}

DONATI, D ^{[1
]}

PERBONI, A ^{[1
]}

ROSSI, T ^{[1
]}

机构：

[1] GLAXO SPA,I-37100 VERONA,ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 04期

关键词：

D O I：

10.1039/c39940000441

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The beta-lactam 4 was linked to the enones 8-10 using a radical reaction mediated by tri-n-butyltin hydride to give the 2,6-disubstituted cyclohexanones 11-16, respectively: 13 was converted into the protected tribactam 18 in two steps.

引用

页码：441 / 442

页数：2

共 9 条

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