SESQUITERPENE QUINONES AS IMMUNOMODULATING AGENTS

被引：24

作者：

BOURGUETKONDRACKI, ML ^{[1
]}

LONGEON, A ^{[1
]}

MOREL, E ^{[1
]}

GUYOT, M ^{[1
]}

机构：

[1] HOP NECKER ENFANTS MALAD,DEPT NEPHROL,CNRS,URA 122,INSERM,U25,F-75743 PARIS 15,FRANCE

来源：

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY | 1991年 / 13卷 / 04期

关键词：

D O I：

10.1016/0192-0561(91)90009-V

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The influence of sesquiterpene quinones and of a sesquiterpene hydroquinone, isolated from the sponge Smenospongia sp. on normal and tumour cells, was investigated. Most showed cytotoxic effects on L1210 leukemia cells. However, their activity on normal cells, such as murine spleen lymphocytes and human peripheral lymphocytes, revealed different behaviours: some of them inhibited, while others enhanced mitogen-stimulated lymphocyte proliferation. These biological studies revealed products modulating immune responses.

引用

页码：393 / 399

页数：7

共 15 条

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