5-FLUOROURACIL NEUROTOXICITY

被引：28
作者：
MOORE, DH
FOWLER, WC
CRUMPLER, LS
机构：
[1] Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill
来源：
GYNECOLOGIC ONCOLOGY | 1990年 / 36卷 / 01期
关键词：
D O I：
10.1016/0090-8258(90)90127-7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Two cases of 5-fluorouracil-induced neurotoxicity from the University of North Carolina are presented. 5-Fluorouracil metabolism is briefly discussed with reference to possible mechanisms for the neurotoxicity. A possible role for thiamine supplementation in the prevention of this unusual complication is supported by our experience. © 1990.
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页码：152 / 154
页数：3
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