Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?

被引:7
作者
Musubire, Abdu K. [1 ,3 ,4 ]
Meya, David B. [1 ,2 ,3 ,4 ]
Lukande, Robert [5 ]
Kambugu, Andrew [1 ,2 ]
Bohjanen, Paul R. [2 ]
Boulware, David R. [2 ]
机构
[1] Makerere Univ, Infect Dis Inst, Coll Hlth Sci, Kampala, Uganda
[2] Univ Minnesota, Dept Med, Div Infect Dis & Int Med, Minneapolis, MN 55455 USA
[3] Makerere Univ, Coll Hlth Sci, Sch Med, Dept Med, Kampala, Uganda
[4] Mulago Hosp, Kampala, Uganda
[5] Makerere Univ, Dept Pathol, Coll Hlth Sci, Kampala, Uganda
来源
MEDICAL MYCOLOGY CASE REPORTS | 2015年 / 8卷
关键词
HIV; AIDS; Cryptococcal meningitis; Cryptococcoma; Antiretroviral therapy; Immune reconstitution inflammatory syndrome;
D O I
10.1016/j.mmcr.2015.03.004
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphaclenopathy, while receiving empiric tuberculosis treatment. Al 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma. (C) 2015 The Authors. International Society for Human and Animal Mycology Published by Elsevier B.V.
引用
收藏
页码:40 / 43
页数:4
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