THE NITRIC OXIDE-SCAVENGING PROPERTIES OF GINKGO-BILOBA EXTRACT EGB-761

被引：731

作者：

MARCOCCI, L

MAGUIRE, JJ

DROYLEFAIX, MT

PACKER, L

机构：

[1] UNIV CALIF BERKELEY,DEPT MOLEC & CELL BIOL,BERKELEY,CA 94720

[2] UNIV CALIF BERKELEY,LAWRENCE BERKELEY LAB,DIV ENERGY & ENVIRONM,BERKELEY,CA 94720

[3] IPSEN,F-75016 PARIS,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 201卷 / 02期

关键词：

D O I：

10.1006/bbrc.1994.1764

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ginkgo biloba extract EGb 761 was found to be a scavenger of nitric oxide in in vitro acellular systems, under physiological conditions. EGb 761 competed with oxyhemoglobin for reaction with nitric oxide generated during the interaction Complex I of catalase. An EGb 761 dose-dependent decrease formed in the reaction of oxygen with nitric oxide produced from nitroprusside was also observed. These data implicate it as a potential therapeutic conditions of altered production of nitric oxide. (C) 1994 Academic Press, Inc.

引用

页码：748 / 755

页数：8

共 40 条

[1] NITRIC-OXIDE ACTIVATES GUANYLATE CYCLASE AND INCREASES GUANOSINE 3'-5'-CYCLIC MONOPHOSPHATE LEVELS IN VARIOUS TISSUE PREPARATIONS [J].