CHOLINESTERASES IN THE AMYLOID ANGIOPATHY OF ALZHEIMERS-DISEASE

被引：27
|
作者：
MESULAM, M
CARSON, K
PRICE, B
GEULA, C
机构：
[1] BETH ISRAEL HOSP,DIV NEUROSCI & BEHAV NEUROL,BULLARD & DENNY BROWN LAB,BOSTON,MA 02215
[2] OLD DOMINION UNIV,DEPT BIOL SCI,ELECTRON MICROSCOPY LAB,NORFOLK,VA 23508
来源：
ANNALS OF NEUROLOGY | 1992年 / 31卷 / 05期
关键词：
D O I：
10.1002/ana.410310517
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Vessels affected by amyloid angiopathy in patients with Alzheimer's disease also displayed intense acetylcholinesterase and butyrylcholinesterase activity when examined by light and electron microscopy. The enzymatic properties of the vessel-bound cholinesterases were identical to those of the cholinesterases associated with senile plaques and neurofibrillary tangles. This cholinesterase activity is of unknown origin but represents one of the very few features common to all the major pathological markers of Alzheimer's disease.
引用
收藏
页码：565 / 569
页数：5
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