FUNCTIONAL MRI OF HUMAN BRAIN ACTIVATION AT HIGH SPATIAL-RESOLUTION

被引：318

作者：

FRAHM, J

MERBOLDT, KD

HANICKE, W

机构：

[1] Max-Planck-Institut Fur Biophysikalische Chemie, Gottingen

来源：

MAGNETIC RESONANCE IN MEDICINE | 1993年 / 29卷 / 01期

关键词：

BRAIN; MR; BLOOD FLOW; FUNCTION; VISUAL CORTEX;

D O I：

10.1002/mrm.1910290126

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Functional activation maps of the human visual cortex were obtained at a spatial resolution almost two orders of magnitude better than achievable by positron emission tomography and within measuring times of a few seconds. Transient alterations in the concentration of paramagnetic deoxyhemoglobin were conveniently detected at 2.0-T with use of RF-spoiled FLASH MRI sequences employing gradient echo times of 6 to 60 ms and voxel sizes of 2.5 to 39 mul.

引用

页码：139 / 144

页数：6

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