LATENT GELATIN SPECIFIC PROTEINASE OF HUMAN-LEUKOCYTES AND ITS ACTIVATION

被引：37

作者：

SOPATA, I

WIZE, J

机构：

[1] Department of Biochemistry, Institute of Rheumatology, Warsaw

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 571卷 / 02期

关键词：

(Human leukocyte); Activation; Gelatinase latent; Gelatinase-inhibitor complex;

D O I：

10.1016/0005-2744(79)90100-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Gelatin specific proteinase (gelatinase) exists in human leucocytes extracts mainly in a latent form. 2. 2. It is activated by different proteinases as well as by some chemicals (urea, NaSCN, HgCl2). 3. 3. Non-proteolytic activation of latent gelatinase and the decreasing of its molecular weight associated with it strongly suggests that it is an enzyme-inhibitor complex. © 1979.

引用

页码：305 / 312

页数：8

共 26 条

[1] EVIDENCE FOR PRESENCE OF A COMPLEX OF COLLAGENASE WITH ALPHA2-MACROGLOBULIN IN HUMAN RHEUMATOID SYNOVIAL-FLUID - POSSIBLE REGULATORY MECHANISM OF COLLAGENASE ACTIVITY IN-VIVO [J].