MONOAMINE OXIDASE, CATECHOL-O-METHYLTRANSFERASE AND PHENYLETHANOLAMINE-N-METHYLTRANSFERASE ACTIVITY IN PARA-AORTIC TISSUE OF HUMAN FETUS

被引:17
作者
GENNSER, G
VONSTUDN.W
机构
[1] Department of Gynecology and Obstetrics and Department of Clinical Chemistry, General Hospital, Malmö University of Lund
关键词
Catechol-O-methyltransferase; Catecholamines; Chromaffin system; Fetus; Methylation; Monoamine oxidase; Phenylethanolamine-N-methyltransferase;
D O I
10.3109/00365516909080148
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Paraganglia of mid-term human fetuses exhibited high monoamine oxidase (MAO) (> in fetal heart and liver), somewhat lower phenylethanolamine-N-methyltransferase (PNMT) (< in fetal adrenals) and no catechol-O-methyltransferase (COMT) activity. The noradrenaline content ranged 115-184 and adrenaline content 2-5 μg/g tissue. The findings indicate that catecholamine inactivation in this organ is performed by MAO and that the adrenaline found is formed locally. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:169 / &
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