OXA-14, ANOTHER EXTENDED-SPECTRUM VARIANT OF OXA-10 (PSE-2) BETA-LACTAMASE FROM PSEUDOMONAS-AERUGINOSA

被引：92
|
作者：
DANEL, F [1 ]
HALL, LMC [1 ]
GUR, D [1 ]
LIVERMORE, DM [1 ]
机构：
[1] UNIV HACETTEPE,SCH MED,DEPT INTERNAL MED,INFECT DIS SECT,ANKARA 06100,TURKEY
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 08期
关键词：
D O I：
10.1128/AAC.39.8.1881
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Pseudomonas aeruginosa 455, isolated in Ankara, Turkey, produced a pI 6.2 beta-lactamase determined by plasmid pMLH53 and resisted all beta-lactams except carbapenems. This beta-lactamase, named OXA-14, corresponded to OXA-10 (PSE-2) except that aspartate replaced glycine at position 157 and thus is intermediate between OXA-10 and OXA-11, which has aspartate at position 157 and a further substitution at position 143.
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页码：1881 / 1884
页数：4
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