BEYOND SIMPLE POOLING FOR HIV SCREENING

被引：5

作者：

GWA, LH

HSIEH, CC

KO, YC

LAN, SJ

机构：

[1] HARVARD UNIV,SCH PUBL HLTH,DEPT EPIDEMIOL,677 HUNTINGTON AVE,BOSTON,MA 02115

[2] NATL TAIWAN UNIV,COLL MED,INST PUBL HLTH,TAIPEI,TAIWAN

[3] KAOHSIUNG MED COLL,SCH PUBL HLTH,KAOHSIUNG,TAIWAN

来源：

JOURNAL OF IMMUNOASSAY | 1992年 / 13卷 / 04期

关键词：

D O I：

10.1080/15321819208019835

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We discuss sonic theoretical features underlying the successful uses of pooling in testing HIV seroprevalence. In particular it is shown that there is a scaling relation for the distribution of positive sera among the pools. A multi-stage pooling method consisting of repeatedly halving the positive pools is proposed. Concentrating on the number of tests required for screening all positive individuals the method is shown to be highly efficient in low prevalence situations.

引用

收藏

页码：545 / 557

页数：13

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